AA on intrinsics w/ side effects

Is there anything that can be used target specific to do AA for intrinsics w/ side effects but no specific memory pointer?

e.g.
instr_custom_A // implicitly only address space A
instr_custom_B // implicitly only address space B

Is there anything in any AA step except e.g. manually propagating alias.scope that would help disambiguating that they are disjoint (in llvm-ir)?

The only idea I have is to add unused pointer arguments to the intrinsics for each memory space that are always null, combined w/ IntrArgMemOnly, maybe additionally handling it then w/ external AA.

Thanks for help

Answering my own question: I think AliasAnalysis::getModRefInfo might do.